Control Panel licenses are activated from central licensing servers. Control Panel periodically connects with licensing server to validate your installed licenses. Once license is validated a local key is generated and your software continues working. During the time local key is valid your software will continue working without dependence on the license server.
You have to make sure that outgoing HTTP calls are allowed from the Control Panel server. If Control Panel is unable to connect to licensing server for over 7 days then it may seize functioning.
If Control Panel primary license server goes down, it will try to backup license server automatically. License servers are geographically distributed and independent of each other.
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